Author information: (1)Faculty of Process and Environmental Engineering, Department of Bioprocess Engineering, Lodz University of Technology, ul.

Conditions for the formation from sucrose of itaconic acid by a strain of Aspergillus terreus have been examined. Itaconic acid production in A. niger. 1.

It is used for the biotechnological production of two valuable metabolites, namely itaconic acid and lovastatin. Aspergillus terreus is the natural producer of itaconic acid.

IA is commercially produced by large-scale submerged fermentations employing the filamentous Ascomycete fungus Aspergillus terreus and using molasses or hydrolized corn starch as primary carbon sources. P. F. Omojasola, E. A. Adeniran . Okabe aspergillus terreus; itaconic acid; biorreactores; acido itaconico; acide.

Aspergillus terreus is a textbook example of an industrially relevant filamentous fungus. Itaconic acid production by Aspergillus terreus from low-cost carbon and nitrogen sources Juliana Cunha da Cruz, Diogo Simas Bernardes Dias, Aline Machado de Castro, Eliana Flávia Camporese Sérvulo . The Production of Itaconic Acid From Sweet Potato Peel Using Aspergillus niger and Aspergillus terreus. Production of lovastatin and itaconic acid by Aspergillus terreus: a comparative perspective.

Itaconic acid (IA), a building block platform chemical, is produced industrially by Aspergillus terreus utilizing glucose. Aspergillus terreus (NRRL 1960) was cultivated in batch and in continuous singlestage culture.

Itaconic acid (2-methylenesuccinic acid; IA) is a five-carbon dicarboxylic acid, frequently used as a building block chemical for the synthesis of plastics, coatings and resins. The production of itaconic acid requires continuous aeration and already a short interruption of oxygen decreases the itaconic acid yield. Aspergillus terreus is successfully used for industrial production of itaconic acid. Itaconic acid (IA), a C5-dicarboxylic acid, has previously been identified as one of the top twelve biochemicals that can be produced by biotechnological means. Indeed, the expression of this gene leads to an increased itaconic acid production. Itaconic acid (IA) production by fermentation of undetoxified hydrolysate of bamboo residues by Aspergillus terreus was demonstrated.

IA is naturally produced by Aspergillus terreus, however, heterologous production in the related species Aspergillus niger has been proposed earlier.

The influence of pH on the growth of the organism, on the formation of itaconic acid and on the kinetics of fermentation was studied under phosphate limitation, both at controlled pH values and also when the pH was allowed to decrease in a natural way.

It has been shown that unrefined cane sugar contains substances favouring the formation of itaconic acid.

Lignocellulosic biomass can serve as a low cost source of sugars for IA production. Itaconic acid production by Aspergillus terreus from low-cost carbon and nitrogen sources 33 www.erpublication.org II. Boruta T(1), Bizukojc M(2). The optimum concentrations of certain mineral components of the medium and some other factors have been investigated. Introduction. Biotechnologically produced itaconic acid is an important building block for the chemical industry and replaces petrochemical-based monomers like acrylic or methacrylic acid for polyesters , .The unsaturated dicarboxylic acid is industrially produced with the filamentous fungus Aspergillus terreus, whereby glucose and sucrose give the highest yields .

Itaconic acid is an important building block for the chemical industry. In order to reduce the sensitivity to oxygen a hemoglobin gene from Vitreoscilla was expressed in A. terreus. It is used for the production of plastics.

MATERIALS AND METHODS A. Microorganism Aspergillus terreus …

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