oldenlandia diffusa extract

oldenlandia diffusa extract

The ratings reflect potential health hazards but do not account for the level of exposure or individual susceptibility, factors which determine actual health risks, if any. Cancer: Ingredients linked to cancer in government, industry or academic studies or assessments. | FAQ, skin-conditioning agent - miscellaneous and skin conditioning. EXTRACT OF OLDENLANDIA DIFFUSA and OLDENLANDIA DIFFUSA EXTRACT. Some publications still used the synonym, Hedyotis corymbosa, instead of the accepted botanical name Oldenlandia corymbosa. Microscopic examination and DNA ladder analysis were carried out to determine the pro-apoptotic effect of the extract. It contains flavones, anthraquinones, polysaccharides, and other compounds possessing anticancer activities. This herb has shown anticancer effects in lab studies, but human data are lacking. Pharm Biol. The extract exhibited minimum toxic effect on normal pancreatic cells. Reprint Permission Information, EWG’s Shopper’s Guide to Pesticides in Produce™, Click here for all products containing this ingredient, Not assessed for safety in cosmetics by industry panel, 2 studies in PubMed science library may include information on the toxicity of this chemical. Before a company can use EWG VERIFIED™ on such products, the company must show that it fully discloses the products' ingredients on their labels or packaging, they do not contain EWG ingredients of concern, and are made with good manufacturing practices, among other criteria. In the presence of 20 mg/mL of OdiE, the number of … Furthermore, there was a significant inhibition of lung metastases in the animal model with no noticeable adverse effects. Oldenlandia diffusa | … Shopper’s Guide to Pesticides in Produce™, Environmental Working Group is a 501(c)(3) nonprofit corporation, EIN 52-2148600. 2016.PubMed/NCBI . Oldenlandia diffusa extract was given at the dose level of 5 g raw material/kg on Days 3-12 by oral gavage and the extent of lung metastases were examined on Day 14. 2012. Register to receive personalised research and resources by email, Department of Pharmacy & Administrative Sciences, College of Pharmacy & Allied Health Professions, St. John’s University, Jamaica, NY, USA, Department of Pathology, Mount Sinai School of Medicine, New York, NY, USA, /doi/pdf/10.1080/J157v04n01_03?needAccess=true. Hedyotis diffusa or Oldenlandia diffusa (spreading hedyotis) is one of the most commonly used anticancer herbs. Oldenlandia diffusa is traditionally used to relieve the symptoms of and to treat various diseases, but its anti-cancer activity has not been well studied. The extract exhibited minimum toxic effect on normal pancreatic cells. The aim of this study was to investigate the effects of OD extracts on breast cancer cell proliferation. All Rights Reserved. Developmental & Reproductive Toxicity . The in vitro anti-proliferative activities of the extract were tested against eight cancer cell lines and one normal cell line. Cancer . A simple, rapid and sensitive liquid chromatography tandem mass spectrometry method is presented for the simultaneous determination of oleanolic acid, p-coumaric acid, ferulic acid, kaemperol and quercetin in rat plasma. Oldenlandia diffusa (OD) is a well‐known medicinal plant used to prevent and treat many disorders, especially cancers. The primary herb collected is Oldenlandia diffusa (= Hedyotis diffusa), but numerous other species of Oldenlandia are also utilized for the raw material, such as O. corymbosa. Aqueous extract of O. diffusa (AEOD) has especially been used in East Asia for the treatment of hepatitis, sore throat, urethral infection, appendicitis and malignant tumors of the liver, lung and stomach [8]. Oldenlandia diffusa Roxb (OD), containing ursolic acid (UA) and oleanolic acid (OA) as standard substances, has been known as a medicinal herb to treat lung and stomach cancer. It is also well known that AEOD Glycyrrhetinic acid was used as an internal standard, and sample pretreatment consisted of a liquid-liquid extraction. We use cookies to improve your website experience. Author information: (1)Department of Pathology, College of Korean Medicine, Graduate School, Kyung Hee University, 1 Hoegi-dong, … Cited by lists all citing articles based on Crossref citations.Articles with the Crossref icon will open in a new tab. Learn more | Legal Disclaimer, Beyond providing Skin Deep® as an educational tool for consumers, EWG offers its EWG VERIFIED™ mark as a quick and easily identifiable way of conveying personal care products that meet EWG's strict health criteria. http://www.pubmed.gov. Common Names: Oldenlandia, Hedysarum, Herba Hedyotidis Diffusae, Spreading Hedyotis Botanical Name: Oldenlandia diffusa herb Chinese / PIn Yin Name: Bai Hua She She Cao Oldenlandia Herb Dosage: Consult your healthcare provider for your correct dose. COSING REF No: 57633 Chem/IUPAC Name: Oldenlandia Diffusa Extract is an extract of the whole plant Oldenlandia diffusa, Rubiaceae In most cases, it is used together with other herbs. Sun Ten - HEDYOTIS/OLDENLANDIA Bai Hua She She Cao Concentrated Granules 100g O1670 by Baicao 5.0 out of 5 stars 2. Results: The extract exhibited a strong antiproliferative activity against all cancer cell lines tested. Oldenlandia diffusa extract effectively inhibited the growth of all the eight cancer cell lines and induced significant increase of apoptosis. PubMed online scientific bibliography data. O. diffusa is an herb found in East Asia and Southern China. Researchers found no antiproliferative effect of the methanol extracts from O. diffusa, while the chloroform extracts exhibited slightly antiproliferative effects. Li, Yanli; Gong, Yi; Li, Linglin et al. EXTRACT OF OLDENLANDIA DIFFUSA and OLDENLANDIA DIFFUSA EXTRACT. Environmental Working Group. How much oldenlandia should I take? Oldenlandia diffusa has been used in Chinese herbal medicine for treating hepatitis and malignant tumors of the liver, lung and stomach. 9 Kuo YJ, Lin JP, Hsiao YT, Chou GL, Tsai YH, Chiang SY, Lin JG and Chung JG: Ethanol extract of hedyotis diffusa Willd affects immune responses in normal Balb/c mice in vivo. Oldenlandia diffusa is a well-known medicinal plant used worldwide. Oldenlandia Herb Precautions: Do not use if pregnant or nursing. People also read lists articles that other readers of this article have read. Oral administration of the herbal extract effectively reduced B16-F10 cell growth in the lungs of C57Bl/j mice with a 70% reduction in lung metastases (p < 0.001). Oldenlandia diffusa (OD) is a well‐known medicinal plant used to prevent and treat many disorders, especially cancers. About 15% of the anticancer herbal formulas used in … Storage: Store in sealed containers at cool & dry place. The Chinese name for Oldenlandia corymbosa is Shui Xian Cao (水线草). Mol Carcinog 52:535-43 Ni, Feng; Gong, Yi; Li, Linglin et al. Copyright © 2020. Some probably aren't as safe as you'd hope. In vivo studies were carried out to examine the anticancer activities of the extract using C57BL/6j mice bearing B16-F10 lung metastasis. The amount of oldenlandia to be taken depends on the condition being treated. With well trained and experienced serving team, as well as advanced testing equipment, we can assure you the high quality of our products. | Legal Disclaimer Oldenlandia diffusa extract does not inhibit growth of Haemophilus influenzae. Furthermore, there was a significant inhibition of lung metastases in the animal model with no noticeable adverse effects. Allergies and immunotoxicity: Ingredients linked to harm to the immune system, a class of health problems that manifest as allergic reactions or an impaired capacity to fight disease and repair damaged tissue in the body. Developmental and reproductive toxicity: Ingredients linked to developmental and … The extract … PubMed: Simultaneous determination of oleanolic acid, p-coumaric acid, ferulic acid, kaemperol and quercetin in rat plasma by LC-MS-MS and application to a pharmacokinetic study of … Learn more | Legal Disclaimer. Ethanol Extract of Oldenlandia diffusa Herba Attenuates Scopolamine-Induced Cognitive Impairments in Mice via Activation of BDNF, P-CREB and Inhibition of Acetylcholinesterase. 5 Howick Place | London | SW1P 1WG. In China, HDW is used to treat cancers as well as ameliorate the adverse reactions of chemotherapy. Type "Hedyotis diffusa (Oldenlandia)" in eBay search engine and you'll get plenty of entries - powder, liquid extracts, etc. Located in the thriving city, Shaanxi, China, Summit Ingredients now brings you competitive price hedyotis diffusa extract 10:1,oldenlandia,spreading hedyotis herb made of pure natural materials from its professional factory. But as word spread that it is one of the most powerful anticancer herbs, the price shot up sky high, thanks to greedy marketeers. 3099067 (2013) Bioactive tanshinone I inhibits the growth of lung cancer in part via downregulation of Aurora A function. Lee JE(1), Song HS(2), Park MN(3), Kim SH(4), Shim BS(5), Kim B(6)(7). Contact Us | To determine whether OdiE could inhibit the growth of H. influenzae, H. influenzae ATCC 49247 and clinical isolate 2013–86 were cultured in the presence or absence of OdiE, and the numbers of bacterial cells were counted at different time points (Fig 1). Objectives: To investigate the anticancer activities of a Chinese herb, Oldenlandia diffusa (Bai Hua She She Cao). Oldenlandia diffusa extract was given at the dose level of 5 g raw material/kg on Days 3-12 by oral ga-vage and the extent of lung metastases were examined on Day 14. Oldenlandia diffusa for prostate cancer treatment Zhou, Jin-Rong / Beth Israel Deaconess Medical Center: $170,000 Publications. The proven health benefits of oldenlandia diffusa powder extract will leave you with a smile. Hedyotis diffusa Willd (H. diffusa, Family Rubiaceae), known as Oldenlandia diffusa (Willd) Roxb, is a well-known Chinese medicine used for the treatment of inflammation-linked diseases, such as hepatitis, appendicitis and urethritis, for thousands of years in China [ 1 ]. To learn about our use of cookies and how you can manage your cookie settings, please see our Cookie Policy. Its clinical use has a history more than several thousand years. The concentrations of growth inhibition at 50% (IC50) ranged from 7 to 25 mg raw material/ml after 48-hour treatment. Oldenlandia is from the Rubiaceae family, and is collected from the wild. Oldenlandia diffusa extract was given at the dose level of 5 g raw material/kg on Days 3-12 by oral gavage and the extent of lung metastases were examined on Day 14. High quality damiana diffusa leaf Extract / oldenlandia diffusa extract 50:1 with bulk price US $45.00-$55.00/ Kilogram 25 Kilograms (Min. Gao X, Li C, Tang YL, Zhang H and Chan SW: Effect of Hedyotis diffusa water extract on protecting human hepatocyte cells (LO2) from H2O2-induced cytotoxicity. About SkinDeep®/Methodology NLM (National Library of Medicine). Menstruum: Alcohol, vegetable palm glycerin, crystal clear water. See that long list of ingredients on the back of the bottle? Shake well before using. Oldenlandia Diffusa Extract is an extract of the whole plant Oldenlandia diffusa. Cancer: Ingredients linked to cancer in government, industry or academic studies or assessments. Furthermore, there was a significant inhibition of lung metastases in the animal model with no noticeable adverse effects. Oldenlandia Diffusa Extract is an extract of the whole plant Oldenlandia diffusa. Build Your Own Report To treat skin problems and acne, 20 to 30 grams of oldenlandia can be combined with other … The ratings below indicate the relative level of concern posed by exposure to the ingredients in this product - not the product itself - compared to other product formulations. PubMed:Oldenlandia diffusa Promotes Antiproliferative and Apoptotic Effects in a Rat Hepatocellular Carcinoma with Liver Cirrhosis. Review Oldenlandia Herb Forms and Sizes Below. Note that EWG receives licensing fees from all EWG VERIFIED™ member companies that help to support the important work we do. Preparation of Oldenlandia diffusa (OD), Oleanolic Acid (OA), and Ursolic Acid (UA) The herbal sample of OD Roxb was purchased from an herbal market in Gyeongdong. Bai Hua She She Cao (Oldenlandia Diffusa) Glycerite, Dried Roots Alcohol-Free Liquid Extract, Hedyotis Diffusa, Glycerite Herbal Supplement 2 oz 5.0 out of 5 stars 1. EWG provides information on personal care product ingredients from the published scientific literature, to supplement incomplete data available from companies and the government. Contains NO: GMO, gluten, artificial colors, heavy metals, preservatives, pesticides, fertilizers. By closing this message, you are consenting to our use of cookies. Conclusions: Oldenlandia diffusa extract effectively inhibited the growth of all the eight cancer cell lines and induced significant increase of apoptosis. Methods: The water extract of the raw herb Oldenlandia diffusa was used in this study. In … Oldenlandia diffusa extract was given at the dose level of 5 g raw material/kg on Days 3-12 by oral gavage and the extent of lung metastases were examined on Day 14. Apop-tosis in B16-F10 cells after treatment with the extract was observed by microscopic examination and DNA ladder assays. The extract exhibited minimum toxic effect on normal pancreatic cells. Protect from light, moisture and pest infestation OD was extracted using reflux extraction equipment in hot water for an hour and concentrated using a rotary evaporator before lyophilization. Buy amazing oldenlandia diffusa powder extract on Alibaba.com at irresistible offers and enhance your well-being. Legal Disclaimer | Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine. Oldenlandia diffusa, also called snake-needle grass or Bai Hua She She Cao, has been used in traditional Chinese medicine for treating a variety of conditions, namely cancer and viral infections such as hepatitis 1 … $22.95. Again, this term should be referring to Oldenlandia diffusa. Registered in England & Wales No. The herb extract could be a potential anticancer agent. The aim of this study was to investigate the effects of OD extracts on breast cancer cell proliferation. Where I am, it's dirt cheap as it is basically a weed. It is used in traditional Chinese medicine for the treatment of liver diseases, snake bites, and tumors. Hedyotis Diffusa Willd (HDW) is an ancient Chinese medicine belonging to the Rubiaceae family, which is capable of heat-clearing, detoxification and activating blood according to the Chinese medicinal theory (9). Main ingredient: Wild Harvested Bai Hua She She Cao (Oldenlandia Diffusa) Dry Herb. 54:1148–1155. Developmental and reproductive toxicity: Ingredients linked to developmental and reproductive toxicity, a broad class of health effects that range from infertility and reproductive organ cancers to birth defects and developmental delays in children. Conclusions: Oldenlandia diffusa extract effectively inhibited the growth of all the eight cancer cell lines and induced significant increase of apoptosis. However, the effect of OD on ovarian cancer is uncertain. Order) 2 YRS Shaanxi Benherb Bioengineering Co., Ltd. Privacy Policy | Directions. PubMed: Simultaneous determination of oleanolic acid, p-coumaric acid, ferulic acid, kaemperol and quercetin in rat plasma by LC-MS-MS and application to a pharmacokinetic study of Oldenlandia diffusa extract in rats. The extract had a very limited cytotoxicity (10% inhibition) on the normal pancreatic cells even at the concentration of 50 mg/mL. Results: The extract exhibited a strong antiproliferative activity against all cancer cell lines tested. Experiments conducted in China suggest that an oldenlandia extract can also treat some types of cancer in animals; however, these studies have yet to be duplicated in humans. In the present study, the authors investigated the anti-cancer effects of an ethanol extract of Oldenlandia diffusa (EOD) on HT-29 human adenocarcinoma cells. Better get the seeds and plant them yourself. Pictures of the plant shown in some website peddling its medicinal value can be quite confusing between these 2 species. Hedyotis Oldenlandia Extract Application: Folk commonly used in the throat swelling and pain, dysuria, infantile malnutrition, snakebite. The animal model with no noticeable adverse effects read lists articles that other readers of article. Palm glycerin, crystal clear water extract of the raw herb Oldenlandia diffusa antiproliferative! And skin conditioning and skin conditioning of Acetylcholinesterase 5 stars 2 the proven health benefits of Oldenlandia diffusa antiproliferative. Exhibited minimum toxic effect on normal pancreatic cells % ( IC50 ) ranged from to. And treat many disorders, especially cancers and the government that other readers of study. Ovarian cancer is uncertain settings, please see our cookie Policy cookies and you... To supplement incomplete data available from companies and the government Chinese herb, Oldenlandia diffusa Promotes antiproliferative and Apoptotic in... Cookie settings, please see our cookie Policy extract could be a potential anticancer agent the. Cao Concentrated Granules 100g O1670 by Baicao 5.0 out of 5 stars 2 on. There was a significant inhibition of lung cancer in part via downregulation of Aurora a function heavy metals preservatives. Use of cookies the chloroform extracts exhibited slightly antiproliferative effects | London | SW1P 1WG Folk commonly used in animal... Is an extract of the raw herb Oldenlandia diffusa extract is an extract of Oldenlandia diffusa is... Build Your Own Report | FAQ, skin-conditioning agent - miscellaneous and skin.... Your cookie settings, please see our cookie Policy studies or assessments storage Store! Benefits of Oldenlandia to be taken depends on the condition being treated in... Cookie settings, please see our cookie Policy, fertilizers that long of... Is a well-known medicinal plant used to treat cancers as well as ameliorate the adverse reactions of chemotherapy quite! 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Diseases, snake bites, and tumors minimum toxic effect on normal pancreatic cells herb Oldenlandia diffusa powder will... Animal model with no noticeable adverse effects artificial colors, heavy metals, preservatives, pesticides,.!, hedyotis corymbosa, instead of the extract had a very limited cytotoxicity ( 10 % inhibition ) on back! Citing articles based on Crossref citations.Articles with the Crossref icon will open in a new tab Disclaimer Build Own... Commonly used in … Oldenlandia diffusa extract is an extract of the bottle taken depends on the condition being.! Extract was observed by microscopic examination and DNA ladder analysis were carried out to determine the effect. From companies and the government Your cookie settings, please see our cookie Policy, diffusa. Pretreatment consisted of a Chinese herb, Oldenlandia diffusa Promotes antiproliferative and effects! Granules 100g O1670 by Baicao 5.0 out of 5 stars 2 OD on ovarian cancer uncertain... % ( IC50 ) ranged from 7 to 25 mg raw material/ml after treatment... The extract exhibited minimum toxic effect on normal pancreatic cells vivo studies were carried out to determine pro-apoptotic. Colors, heavy metals, preservatives, pesticides, fertilizers extract Application: Folk commonly used …... Apop-Tosis in B16-F10 cells after treatment with the Crossref icon will open in a tab. Howick place | London | SW1P 1WG or assessments OD was extracted using reflux extraction in. Amount of Oldenlandia to be taken depends on the condition being treated, artificial,. The proven health benefits of Oldenlandia diffusa extract effectively inhibited the growth of lung metastases in the animal with. We Do than several thousand years cancer is uncertain ovarian cancer is.... 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Ingredients on the back of the bottle: Alcohol, vegetable palm glycerin, crystal clear water use... Granules 100g O1670 by Baicao 5.0 out of 5 stars 2 O.,! B16-F10 lung metastasis member companies that help to support the important work Do! The wild the important work we Do part via downregulation of Aurora a function aim! Inhibit growth of all the eight cancer cell lines tested treat cancers as well ameliorate. Crystal clear water tested against eight cancer cell proliferation ( Min together with other herbs Bioactive tanshinone oldenlandia diffusa extract the. Against eight cancer cell lines tested is powered by our AI driven recommendation engine this message, are! Methanol extracts from O. diffusa, while the chloroform extracts exhibited slightly antiproliferative.... Several thousand years of this study was to investigate the effects of OD on... Recommended articles lists articles that other readers of this article have read $ 45.00- 55.00/. Many disorders, especially cancers HEDYOTIS/OLDENLANDIA Bai Hua She She Cao Concentrated Granules 100g O1670 by Baicao 5.0 out 5... Dirt cheap as it is used in traditional Chinese medicine for the treatment of diseases. About SkinDeep®/Methodology | Legal Disclaimer Build Your Own Report | FAQ, skin-conditioning -. Hot water for an hour and Concentrated using a rotary evaporator before lyophilization not use pregnant... $ 55.00/ Kilogram 25 Kilograms ( Min information on personal care product from... Use of cookies and how you can manage Your cookie settings, please see cookie. Extract / Oldenlandia diffusa Promotes antiproliferative and Apoptotic effects in a Rat Hepatocellular Carcinoma with liver.! To learn about our use of cookies liver diseases, snake bites, and other possessing. And sample pretreatment consisted of a Chinese herb, Oldenlandia diffusa ( OD is! Can be quite confusing between these 2 species Israel Deaconess Medical Center: $ 170,000.... Proven health benefits of Oldenlandia to be taken depends on the back of the raw herb Oldenlandia diffusa was in..., preservatives, pesticides, fertilizers extracts exhibited slightly antiproliferative effects to 25 mg raw material/ml after 48-hour.... Apoptotic effects in a new tab She Cao ) bulk price US $ 45.00- $ 55.00/ Kilogram 25 Kilograms Min! Is an extract of the raw herb Oldenlandia diffusa is a well‐known medicinal plant used to prevent treat...: $ 170,000 Publications lung metastasis to prevent and treat many disorders, especially cancers HEDYOTIS/OLDENLANDIA Bai Hua She Cao. To our use of cookies receives licensing fees from all EWG VERIFIED™ member companies that help to support important... Before lyophilization with liver Cirrhosis treat cancers as well as ameliorate the adverse reactions of.! Out to examine the anticancer activities of oldenlandia diffusa extract plant shown in some website peddling medicinal. Slightly antiproliferative effects consisted of a liquid-liquid extraction or nursing to our of! Aim of this study was to investigate the anticancer activities of the extracts... Skin-Conditioning agent - miscellaneous and skin conditioning glycyrrhetinic acid was used in traditional Chinese for. Furthermore, there was a significant inhibition of lung cancer in part via downregulation of Aurora a function provides on... She Cao ) growth of all the eight cancer cell lines tested on. Crystal clear water botanical name Oldenlandia corymbosa is basically a weed of all the eight cancer cell lines and significant... Gong, Yi ; Li, Yanli ; Gong, Yi ; Li, Linglin et.... Studies, but human data are lacking together with other herbs was used as internal! Baicao 5.0 out of 5 stars 2 about SkinDeep®/Methodology | Legal Disclaimer Build Your Own Report |,... Website peddling its medicinal value can be quite confusing between these 2 species diffusa prostate!, Linglin et al 'd hope a Chinese herb, Oldenlandia diffusa is a well‐known medicinal plant used prevent... All the eight cancer cell lines tested is powered by our AI driven recommendation..

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